The SureComfort Insulin Syringes box comes with a 31 Gauge 3/10cc 5/16 inch needle. There are 100 single use, sterile syringes in this Box. They are FDA approved and Sure Comfort aims to make sure their products are nothing short of top quality. You should consult with your health care professional before using this product to ensure that this is the proper needle and syringe size for your diabetic needs. SureComfort pride themselves on engineering their insulin syringes to be of the utmost comfort, reliability and ease. Savings of over 65%! You should always shop with us first.